Kadalayil, LP and Majumder, K and Mishra, RK and Brahmachari, SK (1988) Sequence specificity of Z-DNA formation in oligonucleotides. In: Biochemistry International, 17 (1). pp. 121-131.Full text not available from this repository.
The sequence specific requirement for B----Z transition in solution was examined in d(CGTGCGCACG), d(CGTACGTACG), d(ACGTACGT) in presence of various Z-inducing factors. Conformational studies show that inspite of the alternating nature of purines and pyrimidines, the aforementioned sequences do not undergo B----Z transition under the influence of NaCl, hexamine cobalt chloride and ethanol. A comparison with the crystal structures of an assorted array of purine and pyrimidine sequences show that the sequence requirement for B----Z transition is much more stringent in solution as compared to the solid state. The disruptive influence of AT base pairs in B to Z transition is discussed.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Academic Press Aust.|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||04 Oct 2010 08:35|
|Last Modified:||04 Oct 2010 08:35|
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