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An Eventful Synthetic Approach Towards the Biologically Potent Natural Product Ottelione A: Enantio-, Regio- and Stereoselective Construction of the Bicyclic Core

Mehta, Goverdhan and Islam, Kabirul (2000) An Eventful Synthetic Approach Towards the Biologically Potent Natural Product Ottelione A: Enantio-, Regio- and Stereoselective Construction of the Bicyclic Core. In: Synlett (10). 1473-1475 .

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Official URL: https://www.thieme-connect.com/ejournals/abstract/...

Abstract

A novel synthetic approach towards the recently reported anti-tumor and anti-tuberculor natural product ottelione A from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone is delineated. Our short strategy, besides being enantio-, regio- and stereoselective, charts an eventful course and is inherently well-suited for adaptation towards diverse synthetic analogues of this biologically potent natural product.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Thieme Medical Publishers.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 30 Sep 2010 09:17
Last Modified: 30 Sep 2010 09:17
URI: http://eprints.iisc.ernet.in/id/eprint/32556

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