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Desensitization to ATP-Mg inhibition of 3-hydroxy-3-methylglutarylCoA reductase by heat treatment of microsomes

George, Rajan and Menon, AS and Ramasarma, T (1978) Desensitization to ATP-Mg inhibition of 3-hydroxy-3-methylglutarylCoA reductase by heat treatment of microsomes. In: Biochemical and Biophysical Research Communications, 84 (3). pp. 544-549.

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Official URL: http://dx.doi.org/10.1016/0006-291X(78)90740-4

Abstract

HMGCoA reductase is found to be inhibited by palmitylCoA and free CoA. The inhibition of this enzyme by ATP-Mg, but not by palmityl CoA, is lost on preincubation of microsomes at 50°C for 15 min.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 08 Oct 2010 11:10
Last Modified: 08 Oct 2010 11:10
URI: http://eprints.iisc.ernet.in/id/eprint/33100

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