Gaikwad, Amos S and Ramasarma, T and Kurup, Ramakrishna CK (1991) Brown adipose tissue mitochondria are cytochrome c — subsaturated. In: Molecular and Cellular Biochemistry, 105 (2). 119 -125.
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The oxidative activity of mitochondria freshly isolated from brown adipose tissue of rats was stimulated two-fold on the addition of small concentrations of exogenous cytochrome c to the reaction medium. Loss of membrane-bound cytochrome c did not occur during isolation of mitochondria. Estimation of the high-affinity binding sites on the organelle membrane indicated that less than a third of these sites remained saturated with cytochrome c. The pigment is thus shown to be a functionally limiting electron transport component in brown adipose tissue.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Springer.|
|Keywords:||BAT mitochondria;electron transport;stimulation;cytochrome c binding sites.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||11 Nov 2010 08:09|
|Last Modified:||11 Nov 2010 08:09|
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