Nagpal, Sunil and Namboodiri, MSA and Rao, Subba BS and Rao, Subba PV (1991) IgG4 Autoantibodies to DNA in Systemic Lupus erythematosus Patients. In: International Archives of Allergy & Applied Immunology, 95 (1). pp. 1-6.Full text not available from this repository.
The presence of DNA-specific IgG4 antibodies was demonstrated in the sera of patients with systemic lupus erythematosus (SLE) by a microtiter solid-phase radioimmunoassay. A patient with distal inter-phalangeal swelling and extensive ulcers in the oral cavity, seronegative for anti-DNA antibodies of the IgG isotype, was found to have anti-DNA autoantibodies exclusively of the IgG4 subclass. These autoantibodies directed against the dsDNA conformation cross-reacted with chondroitin sulfate, dermatan sulfate and heparin.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Karger, Allschwilerstrasse.|
|Keywords:||Subclass Distribution;Antibodies;Serum;Glomerulonephritis; Chromatography;Nephritis;Diseases.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||18 Nov 2010 10:46|
|Last Modified:||18 Nov 2010 10:46|
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