ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Immediate hypersensitivity to Parthenium hysterophorus. II. Clinical studies on the prevalence of parthenium rhinitis

Rao, Sri Rama P and Nagpal, S and Rao, Subba BS and Prakash, OM and Rao, Subba PV (1991) Immediate hypersensitivity to Parthenium hysterophorus. II. Clinical studies on the prevalence of parthenium rhinitis. In: Clinical and Experimental Allergy, 21 (1). 55 -62.

Full text not available from this repository.
Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-...

Abstract

The airborne pollen of the South American weed, Parthenium hysterophorus (American feverfew), accidentally introduced into India was found to be responsible for severe allergic rhinitis. A random clinical survey conducted on 2035 residents of Bangalore city with the aid of questionnaires and skin tests revealed that 7.1% of the study population was suffering from allergic rhinitis due to exposure to Parthenium pollen. Skin-prick tests performed on 1294 clinic patients suffering from nasobronchial allergy during the past 4 years have also shown that 42.5% were sensitive to Parthenium pollen. IgE and IgG antibodies specific for Parthenium pollen allergens were demonstrable in the sera of Parthenium-sensitive rhinitis patients. The specificity of these antibodies to Parthenium allergens was established by ELISA. A 7- to 11-fold higher stimulation was observed when lymphocytes from two Parthenium-sensitive rhinitis patients were treated in vitro with Parthenium pollen extract. To our knowledge, nowhere in the world has such a high incidence of allergic rhinitis due to a single pollen ever been reported.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to John Wiley & Sons.
Keywords: Skin-Test;Radioallergosorbent Test;Allergy;Rast;Reactivity; Invitro;Pollen;Asthma;Assay;Ige.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 19 Nov 2010 06:32
Last Modified: 19 Nov 2010 06:32
URI: http://eprints.iisc.ernet.in/id/eprint/33873

Actions (login required)

View Item View Item