Nair, Murlidharan T and Madhusudan, K and Nagaraja, V and Kulkarni, BD and Majumdar, HK and Singh, Rajan (1996) Theoretical permutation gel electrophoretic analysis of a curved DNA fragment located in circular permutation. In: Electrophoresis, 17 (4). pp. 633-641.
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Using the theoretical model for DNA curvature, we analyzed a set of fragments with a curved insert located in circular permutation. The theoretical permutation analysis of each of the cyclically located fragments reveals the presence of a shifting molecular bend locus. The delineation of the molecular bend locus associated with the fragments obtained by a second permutation helps in providing an explanation for the differential mobility behavior of the fragments.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to John Wiley and Sons.|
|Keywords:||cyclically permuted;cyclically located;dna curvature; theoretical permutation gel electrophoresis|
|Department/Centre:||Division of Biological Sciences > Molecular Reproduction, Development & Genetics (formed by the merger of DBGL and CRBME)|
|Date Deposited:||24 Aug 2005|
|Last Modified:||08 Feb 2012 05:26|
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