Prasad, Kavirayani R and Gandi, Vasudeva Rao (2010) Formal total synthesis of (+)-didemniserinolipid B. In: Tetrahedron: Asymmetry, 21 (23). pp. 2848-2852.
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The formal total synthesis of (+)-didemniserinolipid B, a marine tunicate possessing a 6,8-dioxabicyclo3.2.1]octane framework, was accomplished starting from L-(+)-tartaric acid. The key transformations in the synthesis include the elaboration of a gamma-hydroxy-amide readily obtained by desymmetrization of tartaric acid bis-amide via the controlled addition of a Grignard reagent followed by stereoselective reduction of the resulting ketone. (C) 2010 Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||12 Apr 2011 09:11|
|Last Modified:||12 Apr 2011 09:11|
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