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An unusual distribution of glucose-6-phosphate dehydrogenase deficiency of south Indian newborn population.

Ramadevi, R and Savithri , HS and Devi, AR and Bittles, AH and Rao, NA and UNSPECIFIED (1994) An unusual distribution of glucose-6-phosphate dehydrogenase deficiency of south Indian newborn population. In: Indian Journal of Biochemistry & Biophysics, 31 (4). pp. 358-360.

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Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is seen at a higher frequency in many national and ethnic groups in areas of current or former malaria endemicity. A screening programme undertaken to evaluate the gene frequencies for this deficiency in the highly inbred South Indian population of Karnataka revealed that of the 5140 neonates screened, 7.8% were G6PD deficient with no correlation between the reported level of inbreeding and enzyme deficiency. An interesting finding was the equal number of male (198) and female (207) individuals, with G6PD activity of less than 3 IU. The possible implications of this finding with regard to the expression of G6PD gene is discussed.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to National institute of science communication and information resources.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 10 Jun 2011 04:37
Last Modified: 10 Jun 2011 04:37
URI: http://eprints.iisc.ernet.in/id/eprint/36239

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