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Diastereoselective reduction of α-keto esters derived from functionalised cholic acid

Maltra, U and Packiarajan, M (1994) Diastereoselective reduction of α-keto esters derived from functionalised cholic acid. In: Tetrahedron: Asymmetry, 5 (7). 1171 -1174 .

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Official URL: http://dx.doi.org/10.1016/0957-4166(94)80149-5

Abstract

The reduction of phenylglyoxalate 2a and pyruvate 2b with LiBH4 in THF at -80 degrees C yield the corresponding alpha-hydroxy esters with ca. 70% diastereoselectivity.

Item Type: Editorials/Short Communications
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 02 Jun 2011 05:58
Last Modified: 02 Jun 2011 05:58
URI: http://eprints.iisc.ernet.in/id/eprint/36405

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