Kala, KC and Antony, A (1995) Antibodies raised against guanosine bind to double-stranded DNA. In: Biochemistry & Molecular Biology International, 37 (2). pp. 305-312.Full text not available from this repository.
Antibodies elicited against guanosine have been reported to bind to single-stranded DNA. Using an avidin-biotin microELISA, we report that these antibodies also bind to double-stranded DNA. The binding is specific and is completely inhibited by the homologous hapten. The cross-reactivity of double-stranded DNA binding antibodies to single-stranded DNA is low. The antibodies are shown to bind to the topoisomers of plasmid DNA as assessed by a gel retardation assay.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Academic Press Aust.|
|Department/Centre:||Division of Biological Sciences > Microbiology & Cell Biology|
|Date Deposited:||26 Apr 2011 06:21|
|Last Modified:||26 Apr 2011 06:21|
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