Bhattacharya, Santanu and Subramanian, Marappan and Hiremath, Uma S (1995) Surfactant lipids containing aromatic units produce vesicular membranes with high thermal stability. In: Chemistry and Physics of Lipids, 78 (2). pp. 177-188.
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Six new vesicle-forming, cationic surfactant lipids are synthesized. Four of them contain 'flat' aromatic units at different locations of hydrophobic segments. In order to estimate the influence of aromatic units in the lipid monomer two other surfactant lipids of related structure with n-butyloxy units in the places of aromatic groups were also prepared. Transmission electron microscopy confirmed the vesicular membrane formation from these newly synthesized lipids. DSC or temperature-dependent keto-enol tautomerism of benzoylacetanilide-doped vesicles reveal a remarkable increase in the thermal stability of the membranes formed from aromatic surfactant lipids in contradistinction to their counterparts that contain n-butyloxy units. The enhanced thermal stability originates presumably as a consequence of inter-monomer stacking.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Keywords:||Vesicles;Phase-transition temperatures;Cationic lipids/amphiphiles;Stacking interactions|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||26 May 2011 06:10|
|Last Modified:||26 May 2011 06:10|
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