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Synthetic studies directed towards the potent cytotoxic natural product ottelione A: stereoselective construction of the complete framework

Mehta, Goverdhan and Reddy, Srinivasa D (1999) Synthetic studies directed towards the potent cytotoxic natural product ottelione A: stereoselective construction of the complete framework. In: Chemical Communications (21). pp. 2193-2194.

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Abstract

A stereoselective strategy for the rapid acquisition of the complete framework (dideoxyottelione A) of the promising cytotoxic agent ottelione A, with four contiguous stereogenic centres on a hydrindane skeleton and a sensitive 4-methylenecyclohex-2-enone functionality, from the readily available Diels-Alder adduct of 1,2,3,4-tetrachloro-5,5-dimethoxycyclopentadiene and norbornadiene, is delineated.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Royal Society of Chemistry.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 02 Jul 2011 06:19
Last Modified: 02 Jul 2011 06:19
URI: http://eprints.iisc.ernet.in/id/eprint/38836

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