Pal, Debjani and Venkataraman, V (2002) A portable battery-operated chip thermocycler based on induction heating. In: Sensors and Actuators A: Physical, 102 (1-2). pp. 151-156.
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A microchip thermocycler, fabricated from silicon and Pyrex #7740 glass, is described. Usual resistive heating has been replaced by induction heating, leading to much simpler fabrication steps. Heating and cooling rates of 6.5 and 4.2 degreesC/s, respectively have been achieved, by optimising the heater dimensions and heating frequency (similar to200 kHz). Four devices are mounted on a heater, resulting in low power consumption (similar to 1.4 W per device on the average). Using simple on-off electronic temperature control, a temperature stability within -0.2 degreesC is achieved. Features such as induction heating, good temperature control, battery operation, and low power consumption make the device suitable for portable applications, particularly in polymerase chain reaction (PCR) systems. (C) 2002 Elsevier Science B.V. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Keywords:||Microfabrication;PCR;Induction heating;Low power;Thermocycler|
|Department/Centre:||Division of Physical & Mathematical Sciences > Physics|
|Date Deposited:||04 Aug 2011 05:34|
|Last Modified:||04 Aug 2011 05:34|
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