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Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis

Bhat, Ramakrishna G and Kerouredan, Erwan and Porhiel, Emmanuel and Chandrasekaran, Srinivasan (2002) Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis. In: Tetrahedron Letters, 43 (13). pp. 2467-2469.

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Official URL: http://dx.doi.org/10.1016/S0040-4039(02)00287-3

Abstract

Propargyl pentafluorophenyl carbonate was synthesised in quantitative yield by the reaction of propargyl chloroformate and pentafluorophenol. All the N-propargyloxycarbonyl (N-Poc) amino acids were obtained in good yield. The use of Poc-OPfp in peptide synthesis has been explored. (C) 2002 Elsevier Science Ltd. All rights reserved.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 28 Jul 2011 04:43
Last Modified: 28 Jul 2011 04:43
URI: http://eprints.iisc.ernet.in/id/eprint/39440

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