ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Acylation of Grignard reagents mediated by N-methylpyrrolidone: A remarkable selectivity for the synthesis of ketones

Gowda, Maravanhalli Sidde and Pande, Sushanth Sudhir and Ramakrishna, Ramesha Andagar and Prabhu, Kandikere Ramaiah (2011) Acylation of Grignard reagents mediated by N-methylpyrrolidone: A remarkable selectivity for the synthesis of ketones. In: Organic and Biomolecular Chemistry, 9 (15). pp. 5365-5368.

[img] PDF
Acylation_of_Grignard.pdf - Published Version
Restricted to Registered users only

Download (202Kb) | Request a copy
Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2011...

Abstract

An efficient user-friendly method of acylation of Grignard reagents to selectively synthesize ketones is presented, which is assisted by simple amides such as NMP, or DMF. The present chemoselective method tolerates a variety of functional groups such as ketone, ester, nitrile and other functional groups.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Royal Society of Chemistry.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 04 Aug 2011 11:05
Last Modified: 04 Aug 2011 11:05
URI: http://eprints.iisc.ernet.in/id/eprint/39746

Actions (login required)

View Item View Item