Gowda, Maravanhalli Sidde and Pande, Sushanth Sudhir and Ramakrishna, Ramesha Andagar and Prabhu, Kandikere Ramaiah (2011) Acylation of Grignard reagents mediated by N-methylpyrrolidone: A remarkable selectivity for the synthesis of ketones. In: Organic and Biomolecular Chemistry, 9 (15). pp. 5365-5368.
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An efficient user-friendly method of acylation of Grignard reagents to selectively synthesize ketones is presented, which is assisted by simple amides such as NMP, or DMF. The present chemoselective method tolerates a variety of functional groups such as ketone, ester, nitrile and other functional groups.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Royal Society of Chemistry.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||04 Aug 2011 11:05|
|Last Modified:||04 Aug 2011 11:05|
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