Enantiospecific synthesis of functionalised bicyclo[3.3.1] nonanes from 10-bromocarvones via tandem intermolecular alkylation-intramolecular Michael addition sequence

Srikrishna, A and Kumar, PP and Reddy, TJ (2003) Enantiospecific synthesis of functionalised bicyclo[3.3.1] nonanes from 10-bromocarvones via tandem intermolecular alkylation-intramolecular Michael addition sequence. In: ARKIVOC (part 3). pp. 55-66.

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Abstract

A simple and convenient tandem methodology for the enantiospecific generation of functionalised bicyclo[3.3.1] nonanes 9,14-18, via intermolecular alkylation of Michael donors with 10-bromocarvones 7, 10 and 11, followed by intramolcular Michael addition, is achieved. An unsuccessful attempt for the extension of the methodology for a possible short enantiospecific approach to AB-ring system 22 of taxanes via the allyl bromide 21, is also described.

Item Type:	Journal Article
Additional Information:	Copyright of this article belongs to Arkat USA Inc.
Department/Centre:	Others
Date Deposited:	29 Aug 2011 08:00
Last Modified:	29 Aug 2011 08:00
URI:	http://eprints.iisc.ernet.in/id/eprint/40086

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