Mehta, Goverdhan and Ramesh, Senaiar S (2004) Enantioselective total synthesis of (+)-panepophenanthrin, a novel inhibitor of the ubiquitin-activating enzyme. In: Tetrahedron Letters, 45 (9). pp. 1985-1987.
An enantioselective total synthesis of the novel natural product (+)-panepophenanthrin has been accomplished in which a biomimetic Diels–Alder dimerisation is a key step. The monomeric precursor 2 was assembled from the readily available Diels–Alder adduct of cyclopentadiene and p-benzoquinone through a short, simple sequence employing chemo- and stereoselective operations.
|Item Type:||Journal Article|
|Additional Information:||Copyright for this article belongs to Elsevier Science Ltd.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||22 Jun 2004|
|Last Modified:||19 Sep 2010 04:12|
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