Enantioselective total synthesis of (+)-panepophenanthrin, a novel inhibitor of the ubiquitin-activating enzyme

Mehta, Goverdhan and Ramesh, Senaiar S (2004) Enantioselective total synthesis of (+)-panepophenanthrin, a novel inhibitor of the ubiquitin-activating enzyme. In: Tetrahedron Letters, 45 (9). pp. 1985-1987.

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Abstract

An enantioselective total synthesis of the novel natural product (+)-panepophenanthrin has been accomplished in which a biomimetic Diels–Alder dimerisation is a key step. The monomeric precursor 2 was assembled from the readily available Diels–Alder adduct of cyclopentadiene and p-benzoquinone through a short, simple sequence employing chemo- and stereoselective operations.

Item Type:	Journal Article
Additional Information:	Copyright for this article belongs to Elsevier Science Ltd.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	22 Jun 2004
Last Modified:	19 Sep 2010 04:12
URI:	http://eprints.iisc.ernet.in/id/eprint/412

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