ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Simulation of RNA silencing pathway for time-dependent transgene transcription rate

Yang, Xiao-Dong and Roy Mahapatra, Debiprosad and Melnik, Roderick VN (2007) Simulation of RNA silencing pathway for time-dependent transgene transcription rate. In: AIP Conf. Proc., 952.

Full text not available from this repository.
Official URL: http://scitation.aip.org/getabs/servlet/GetabsServ...

Abstract

The synthesis of dsRNA is analyzed using a pathway model with amplifications caused by the aberrant RNAs. The transgene influx rate is assumed time-decaying considering the fact that the number of transgenes can not be infinite. The dynamics of the transgene induced RNA silencing is investigated using a system of coupled nonautonomous ordinary nonlinear differential equations which describe the model phenomenologically. The silencing phenomena are detected after a period of transcription. Important contributions of certain parameters are discussed with several numerical examples.

Item Type: Conference Paper
Additional Information: Copyright of this article belongs to American Institute of Physics.
Keywords: macromolecules;computer aided analysis;nonlinear differential equations
Department/Centre: Division of Mechanical Sciences > Aerospace Engineering (Formerly, Aeronautical Engineering)
Date Deposited: 22 Oct 2011 07:34
Last Modified: 22 Oct 2011 07:34
URI: http://eprints.iisc.ernet.in/id/eprint/41595

Actions (login required)

View Item View Item