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Enhanced endocytosis of nano-curcumin in nasopharyngeal cancer cells: An atomic force microscopy study

Prasanth, R and Nair, Greshma and Girish, CM (2011) Enhanced endocytosis of nano-curcumin in nasopharyngeal cancer cells: An atomic force microscopy study. In: Applied Physics Letters, 99 (16).

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Abstract

Recent studies in drug development have shown that curcumin can be a good competent due to its improved anticancer, antioxidant, anti-proliferative, and anti-inflammatory activities. A detailed real time characterization of drug (curcumin)-cell interaction is carried out in human nasopharyngeal cancer cells using atomic force microscopy. Nanocurcumin shows an enhanced uptake over micron sized drugs attributed to the receptor mediated route. Cell membrane stiffness plays a critical role in the drug endocytosis in nasopharyngeal cancer cells. (C) 2011 American Institute of Physics. [doi:10.1063/1.3653388]

Item Type: Journal Article
Additional Information: Copyright of this article belongs to American Institute of Physics.
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Date Deposited: 07 Dec 2011 06:35
Last Modified: 07 Dec 2011 06:35
URI: http://eprints.iisc.ernet.in/id/eprint/42532

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