Kumar, Vinod and Rana, Hemlata and Sankolli, Ravish and Kaushik, MP (2012) Novel and efficient protocol for the syntheses of N-1 substituted thiohydantoin and a bicyclothiohydantoin under solvent-free conditions. In: Tetrahedron Letters, 53 (19). pp. 2377-2379.
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A novel approach for the synthesis of N-1 substituted thiohydantoin has been developed to give quantitative yields of the desired products. The efficient synthesis of bis-thiohydantoin derivative and bicyclothiohydantoin has extended scope and applicability of present method. Solvent-free conditions and very easy work-up procedure make the reaction convenient and eco-friendly. All the products were characterized by spectroscopic techniques and elemental analysis, and finally the structure of representative ;compound was also confirmed by X-ray crystallography. (C) 2012 Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article is belongs to Elsevier Science.|
|Keywords:||Thiohydantoin;Methyl N-cyano-N-alkyl/arylaminoacetate; Bicyclothiohydantoin and bis-thiohydantoin; Diethylthiophosphate;Solvent-free conditions|
|Department/Centre:||Division of Chemical Sciences > Solid State & Structural Chemistry Unit|
|Date Deposited:||21 Aug 2012 03:48|
|Last Modified:||21 Aug 2012 03:48|
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