Prasad, Kavirayani R and Nidhiry, John E. (2012) Total Synthesis of (+)-Eburnamonine. In: SYNLETT, 23 (10). pp. 1477-1480.
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Official URL: http://dx.doi.org/10.1055/s-0031-1291143
Abstract
The enantiospecific total synthesis of vinca alkaloid (+)-eburnamonine is accomplished from L-ethyl lactate. Key feature of the synthesis is the construction of the chiral quaternary center involving a Johnson-Claisen rearrangement and assembly of the pentacyclic core by the Pictet-Spengler reaction and ring-closing metathesis.
| Item Type: | Journal Article |
|---|---|
| Additional Information: | Copyright for this article belongs to Georg Thieme Verlag KG |
| Keywords: | eburnamonine; alkaloids; L-ethyl lactate |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 23 Jul 2012 12:13 |
| Last Modified: | 23 Jul 2012 12:15 |
| URI: | http://eprints.iisc.ernet.in/id/eprint/44808 |
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