Bindu, PJ and Mahadevan, KM and Naik, Ravikumar TR (2012) Sm(III)nitrate-catalyzed one-pot synthesis of furano3,2c]-1,2,3,4-tetrahydroquinolines and DNA photocleavage studies. In: JOURNAL OF MOLECULAR STRUCTURE, 1020 . pp. 142-147.
jou_mol_str_1020_142-147_2012.pdf - Published Version
Restricted to Registered users only
Download (724Kb) | Request a copy
The synthesis and DNA photocleavage studies of furano3,2-c]-1,2,3,4-tetrahydroquinolines have been reported. Sm(III)nitrate was found to be an efficient for the Diels-Alder reaction of aryl amines with 2,3-dihydrofuran to offer the corresponding furano3,2-c]-1,2,3,4-tetrahydroquinolines derivatives as a mixture of cis/trans stereoisomers in moderate yields. The aqueous solubility of acid catalyst can be recycled without significant loss of activity. The DNA photocleavage studies shows that, the cis/trans stereoisomers are good DNA cleavage mimic in terms of molecular structure. (C) 2012 Elsevier B.V. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright for this article belongs to Elsevier|
|Keywords:||Sm(III)nitrate; Furano3,2-c]-1,2,3,4-tetrahydroquinolines; DNA; Photocleavage|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||08 Aug 2012 08:41|
|Last Modified:||08 Aug 2012 08:41|
Actions (login required)