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A versatile resolving agent for diffusion edited separation of enantiomers, complex mixtures and constitutional isomers

Chaudhari, Sachin Rama and Srinivasa, * and Suryaprakash, N (2012) A versatile resolving agent for diffusion edited separation of enantiomers, complex mixtures and constitutional isomers. In: RSC Advances, 2 (23). pp. 8689-8692.

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Official URL: http://dx.doi.org/10.1039/C2RA20982A

Abstract

The study is the first report of the utilization of a crown ether as a new and versatile resolving agent for the diffusion edited separation of enantiomers, complex mixtures and constitutional isomers. As a consequence of different binding affinities of enantiomers of a chiral molecule and individual components of the complex mixtures with the crown ether, the molecules diffuse at different rates. The enhanced separation achieved due to matrix assisted diffusion permitted their separation in the diffusion dimension. The generality and wide utility of the new resolving agent and the methodology are demonstrated on diverse examples, such as an organic chiral molecule, constitutional isomers and complex mixture of molecules possessing different functional groups that possess nearly identical molecular weights.

Item Type: Journal Article
Additional Information: Copyright for this article is belongs to Royal society of chemistry.
Keywords: PERFORMANCE LIQUID-CHROMATOGRAPHY; CONTAINING MOBILE PHASES;ORDERED SPECTROSCOPY;NMR-SPECTROSCOPY;CROWN-ETHER; STATIONARY PHASES;NEUTRAL MOLECULES;3D DOSY;RESOLUTION; TOOL
Department/Centre: Division of Chemical Sciences > NMR Research Centre (Formerly SIF)
Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited: 07 Dec 2012 09:23
Last Modified: 07 Dec 2012 09:23
URI: http://eprints.iisc.ernet.in/id/eprint/45213

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