Madan, Ranjna and Kolter, Roberto and Mahadevan, S (2005) Mutations That Activate the Silent bgl Operon of Escherichia coli Confer a Growth Advantage in Stationary Phase. In: Journal of Bacteriology, 187 (23). pp. 7912-7917.
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Wild-type strains of Escherichia coli are unable to utilize aromatic beta-glucosides such as arbutin and salicin because the major genetic system that encodes the functions for their catabolism, the bgl operon, is silent and uninducible. We show that strains that carry an activated bgl operon exhibit a growth advantage over the wild type in stationary phase in the presence of the rpoS819 allele that causes attenuated rpoS regulon expression. Our results indicate a possible evolutionary advantage in retaining the silent bgl operon by wild-type bacteria.
|Item Type:||Journal Article|
|Additional Information:||Copyright for this article belongs to American Society for Microbiology.|
|Department/Centre:||Division of Biological Sciences > Molecular Reproduction, Development & Genetics (formed by the merger of DBGL and CRBME)|
|Date Deposited:||18 Jan 2006|
|Last Modified:||08 Dec 2010 10:29|
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