Kumar, Anil (2003) Two-dimensional nuclear Overhauser effect experiment in a protein: the first NOESY (1979-80). In: Magnetic Resonance in Chemistry, 41 (S1). S26-S32.
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The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a seminal development in the algorithm of protein structure determination by liquid-state NMR. This article provides a historical and personal view of the various facilities, challenges and solutions in the successful development of this experiment for biomolecules in Professor Wuthrich's laboratory during the academic year 1979-80.
|Item Type:||Journal Article|
|Additional Information:||The copyright belongs to John Wiley & Sons, Ltd.|
|Keywords:||two dimensional nmr;noesy;cosy;proton proton noe;proteins; biomolecules;secondary structure;three dimensional structure; liquid state nmr|
|Department/Centre:||Division of Chemical Sciences > Sophisticated Instruments Facility
Division of Physical & Mathematical Sciences > Physics
|Date Deposited:||28 Feb 2006|
|Last Modified:||19 Sep 2010 04:23|
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