Srikrishna, A and Viswajanani, R and Sattigeri, JA (2003) A radical cyclisation based cyclopentenone annulation of allyl alcohols. In: Tetrahedron: Asymmetry, 14 (19). pp. 2975-2983.
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A four-step cyclopentenone annulation reaction of allylic alcohols employing a 5-exo-trig radical cyclisation reaction of mixed allyl methyl ketals of bromoacetone as the key step is described. The annulated product 12b obtained from 2,3-dimethylcyclohexenol has been further elaborated into (±)-epibakkenolides employing a 5-exo-dig radical cylisation reaction based \alpha-spiro-\beta-methylene-\gamma-butyrolactone annulation methodology.
|Item Type:||Journal Article|
|Additional Information:||The Copyright belongs to Elsevier.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||09 May 2006|
|Last Modified:||19 Sep 2010 04:26|
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