Prasad, Kavirayani R and Gholap, Shivajirao L (2006) Stereoselective Synthesis of (+)-Goniothalesdiol. In: Journal of Organic chemistry, 71 (9). pp. 3643-3645.
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Stereoselective synthesis of antitumor tetrahydrofuran (+)-goniothalesdiol was achieved in high overall yield from (-)-D-tartaric acid. Key features include an $FeCl_3$ mediated THF formation with very high selectivity. Synthesis of natural gonithalesdiol and its analogue 2,5-bis-epi-goniothalesdiol was achieved from a common intermediate.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to American chemical Society.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||17 May 2006|
|Last Modified:||19 Sep 2010 04:26|
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