Srikrishna, A and Lakshmi, Vasantha B and Mathews, Manoj (2006) Construction of spiro[5.5]undecanes containing a quaternary carbon atom adjacent to a spirocentre via an Ireland ester Claisen rearrangement and RCM reaction sequence. Total syntheses of (±)-$\alpha$-chamigrene, (±)-$\beta$-chamigrene and (±)-laurencenone C. In: Tetrahedron Letters, 47 (13). pp. 2103-2106.
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Starting from cyclohexanecarboxylic acid, a combination of an Ireland ester Claisen rearrangement and RCM reactions was exploited for an eﬃcient construction of spiro[5.5]undecanes containing a quaternary carbon atom adjacent to the spirocentre and the methodology was extended to complete total syntheses of three chamigrenes.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||31 May 2006|
|Last Modified:||19 Sep 2010 04:28|
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