Selvaraj, M and Singh, NS and Roy, Siddhartha and Sangeetha, R and Varshney, Umesh and Vijayan, M (2006) Cloning, expression, purification, crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis. In: Acta Crystallographica Section F, 62 (9). pp. 913-915.
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Peptidyl-tRNA hydrolase catalyses the cleavage of the ester link between the peptide and the tRNA in peptidyl-tRNAs that, for various reasons, have dropped off the translating ribosomes. This enzyme from Mycobacterium tuberculosis has been crystallized in three related but distinct forms: $P2_12_12_1$, unit-cell parameters a = 36.30, b = 61.85, c = 73.97 \AA , $P2_1$, a = 35.83, b = 73.79, c = 59.79 \AA ,$_\beta$ = 92.3, and $P2_12_12_1$, a = 35.84, b = 57.06, c = 72.59 \AA . X-ray data have been collected from all three forms.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to International Union of Crystallography.|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit
Division of Biological Sciences > Microbiology & Cell Biology
|Date Deposited:||21 Nov 2006|
|Last Modified:||19 Sep 2010 04:32|
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