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Number of items: 45.

Journal Article

Srinivasan, Bharath and Forouhar, Farhad and Shukla, Arpit and Sampangi, Chethana and Kulkarni, Sonia and Abashidze, Mariam and Seetharaman, Jayaraman and Lew, Scott and Mao, Lei and Acton, Thomas B. and Xiao, Rong and Everett, John K and Montelione, Gaetano T and Tong, Liang and Balaram, Hemalatha (2014) Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. In: FEBS JOURNAL, 281 (6). pp. 1613-1628.

Williams, Sunanda Margrett and Chandran, Anu V and Vijayabaskar, Mahalingam S and Roy, Sourav and Balaram, Hemalatha and Vishveshwara, Saraswathi and Vijayan, Mamannamana and Chatterji, Dipankar (2014) A Histidine Aspartate Ionic Lock Gates the Iron Passage in Miniferritins from Mycobacterium smegmatis. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 289 (16). pp. 11042-11058.

Banerjee, Sanchari and Agrawal, Monika J and Mishra, Diptimayee and Sharan, Siddharth and Balaram, Hemalatha and Savithri, Handanhal S and Murthy, Mathur RN (2014) Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme. In: FEBS JOURNAL, 281 (6). pp. 1642-1658.

Ali, Rustam and Kumar, Sanjeev and Balaram, Hemalatha and Sarma, Siddhartha P (2013) Solution nuclear magnetic resonance structure of the GATase subunit and structural Basis of the interaction between GATase and ATPPase subunits in a two-subunit-type GMPS from methanocaldococcus jannaschii. In: Biochemistry, 52 (25). pp. 4308-4323.

Ali, Rustam and Kumar, Sanjeev and Balaram, Hemalatha and Sarma, Siddhartha P (2012) H-1, C-13, N-15 assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii. In: BIOMOLECULAR NMR ASSIGNMENTS, 6 (2). pp. 193-196.

Samanta, Moumita and Murthy, MRN and Balaram, Hemalatha and Balaram, Padmanabhan (2011) Revisiting the Mechanism of the Triosephosphate Isomerase Reaction: The Role of the Fully Conserved Glutamic Acid 97 Residue. In: ChemBioChem, 12 (12). pp. 1885-1895.

Samanta, Moumita and Banerjee, Mousumi and Murthy, Mathur RN and Balaram, Hemalatha and Balaram, Padmanabhan (2011) Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis - distal effects on dimer stability. In: FEBS Journal, 278 (11). pp. 1932-1943.

Samanta, Moumita and Banerjee, Mousumi and Murthy, Mathur RN and Balaram, Hemalatha and Balaram, Padmanabhan (2011) Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis - distal effects on dimer stability. In: FEBS Journal, 278 (11). pp. 1932-1943.

Banerjee, Mousumi and Balaram, Hemalatha and Joshi, NV and Balaram, P (2011) Engineered dimer interface mutants of triosephosphate isomerase: the role of inter-subunit interactions in enzyme function and stability. In: Protein Engineering Design and Selection, 24 (5). pp. 463-472.

Bulusu, Vinay and Thakur, Suman S and Venkatachala, Roopa and Balaram, Hemalatha (2011) Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). In: Molecular and Biochemical Parasitology, 177 (1). pp. 1-11.

Bhat, Javaid Yousuf and Venkatachala, Roopa and Singh, Kavita and Gupta, Kallol and Sarma, Siddhartha P and Balaram, Hemalatha (2011) Ammonia Channeling in Plasmodium falciparum GMP Synthetase: Investigation by NMR Spectroscopy and Biochemical Assays. In: Biochemistry, 50 (16). pp. 3346-3356.

Mehrotra, Sonali and Mylarappa, BN and Iyengar, Prathima and Balaram, Hemalatha (2010) Studies on active site mutants of P-falciparum adenylosuccinate synthetase: Insights into enzyme catalysis and activation. In: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1804 (10). pp. 1996-2002.

Chakrabarty, Subhra Prakash and Ramapanicker, Ramesh and Mishra, Roli and Chandrasekaran, Srinivasan and Balaram, Hemalatha (2009) Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity. In: Bioorganic & Medicinal Chemistry, 17 (23). pp. 8060-8072.

Banerjee, Mousumi and Balaram, Hemalatha and Balaram, Padmanabhan (2009) Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase.The role of conserved residues and complementary mutations. In: FEBS Journal, 276 (15). pp. 4169-4183.

Gayathri, P and Banerjee, Mousumi and Vijayalakshmi, A and Balaram, Hemalatha and Balaram, P and Murthy, MRN (2009) Biochemical and structural characterization of residue 96 mutants of Plasmodium falciparum triosephosphate isomerase: active-site loop conformation, hydration and identification of a dimer-interface ligand-binding site. In: Acta Crystallographica Section D-Biological Crystallography, 65 (8). pp. 847-857.

Gayathri, P and Subbayya, IN Sujay and Ashok, Chethan S and Selvi, T Senthamizh and Balaram, Hemalatha and Murthy, MRN (2008) Crystal structure of a chimera of human and plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization. In: Proteins-Structure Function and Bioinformatics, 73 (4). pp. 1010-1020.

Chakrabarty, Subhra Prakash and Saikumari, Yegnisettipalli Krishnaiah and Bopanna, Monnanda P and Balaram, Hemalatha (2008) Biochemical characterization of Plasmodium falciparum Sir2,a $NAD^+$-dependent deacetylase. In: Molecular and Biochemical Parasitology, 158 (2). pp. 139-151.

Gayathri, P and Balaram, Hemalatha and Murthy, MRN (2007) Structural biology of plasmodial proteins. In: Current Opinion in Structural Biology, 17 (6). pp. 744-754.

Sabareesh, V and Ranganayaki, RS and Raghothama, S and Bopanna, MP and Balaram, Hemalatha and Srinivasan, MC and Balaram, Padmanabhan (2007) Identification and characterization of a library of microheterogeneous cyclohexa-depsipeptides from the fungus. In: Journal of Natural Products, 70 (5). pp. 715-729.

Sabareesh, V and Ranganayaki, RS and Raghothama, Srinivasarao and Bopanna, MP and Balaram, Hemalatha and Srinivasan, MC and Balaram, P (2007) Identification and characterization of a library of microheterogeneous cyclohexadepsipeptides from the fungus Isaria. In: Journal of Natural Products, 70 (5). pp. 715-729.

Gayathri, P and Banerjee, Mousumi and Vijayalakshmi, A and Azeez, Shamina and Balaram, Hemalatha and Balaram, P and Murthy, MRN (2007) Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii. In: Acta Crystallographica Section D-Biological Crystallography, 63 (2). pp. 206-220.

Parthasarathy, Sampathkumar and Eaazhisai, Kandiah and Balaram, Hemalatha and Balaram, Padmanabhan and Murthy, Mathur RN (2003) Structure of Plasmodium falciparum Triose-phosphate Isomerase-2-Phosphoglycerate Complex at 1.1-Å Resolution. In: Journal of Biological Chemistry, 278 (52). pp. 52461-52470.

Pattanaik, Priyaranjan and Jain, Bimba and Ravindra, Gudihal and Gopi, Hosahudya N and Pal, Prajna P and Balaram, Hemalatha and Balaram, Padmanabhan (2003) Stage-specific profiling of Plasmodium falciparum proteases using an internally quenched multispecificity protease substrate. In: Biochemical and Biophysical Research Communications, 309 (4). pp. 974-979.

Pattanaik, Priyaranjan and Ravindra, Gudihal and Sengupta, Chandana and Maithal, Kapil and Balaram, Padmanabhan and Balaram, Hemalatha (2003) Unusual fluorescence of W168 in Plasmodium falciparum triosephosphate isomerase, probed by single-tryptophan mutants. In: European Journal of Biochemistry, 270 (4). pp. 745-756.

Gopi, Hosahudya N and Ravindra, Gudihal and Pal, Prajna P and Pattanaik, Priyaranjan and Balaram, Hemalatha and Balaram, Padmanabhan (2003) Proteolytic stability of beta-peptide bonds probed using quenched fluorescent substrates incorporating a hemoglobin cleavage site. In: FEBS Letters, 535 (1-3). pp. 175-178.

Parthasarathy, S and Balaram, Hemalatha and Balaram, P and Murthy, MRN (2002) Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state. In: Acta Crystallographica Section D: Biological Crystallography, 58 (12). pp. 1992-2000.

Parthasarathy, S and Ravindra, G and Balaram, Hemalatha and Balaram, P and Murthy, MRN (2002) Structure of the Plasmodium falciparum Triosephosphate Isomerase-Phosphoglycolate Complex in Two Crystal Forms: Characterization of Catalytic Loop Open and Closed Conformations in the Ligand-Bound State. In: Biochemistry, 41 (44). 13178 -13188.

Maithal, Kapil and Ravindra, Gudihal and Balaram, Hemalatha and Balaram, Padmanabhan (2002) Inhibition of Plasmodium falciparum Triose-phosphate Isomerase by Chemical Modification of an Interface Cysteine: Electrospray Ionization Mass Spectrometric Analysis of Differential Cysteine Reactivities. In: Journal of Biological Chemistry, 277 (28). pp. 25106-25114.

Maithal, Kapil and Ravindra, Gudihal and Nagaraj, G and Singh, Kumar S and Balaram, Hemalatha and Balaram, P (2002) Subunit interface mutation disrupting an aromatic cluster in Plasmodium falciparum triosephosphate isomerase: effect on dimer stability. In: Protein Engineering, 15 (7). pp. 575-584.

Singh, Kumar S and Maithal, Kapil and Balaram, Hemalatha and Balaram, P (2001) Synthetic peptides as inactivators of multimeric enzymes: inhibition of Plasmodium falciparum triosephosphate isomerase by interface peptides. In: FEBS Letters, 501 (1). pp. 19-23.

Nagaraj, G and Uma, MV and Shivayogi, MS and Balaram, Hemalatha (2001) Antimalarial Activities of Peptide Antibiotics Isolated from Fungi. In: Antimicrobial Agents And Chemotherapy, 45 (1). pp. 145-149.

Ray, Soumya S and Balaram, Hemalatha and Balaram, P (1999) Unusual stability of a multiply nicked form of Plasmodium falciparum triosephosphate isomerase. In: Chemistry and Biology, 6 (9). pp. 625-637.

Gokhale, RS and Ray, Soumya S and Balaram, Hemalatha and Balaram, Padmanabhan (1998) Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride solutions. Evidence for a novel disulfide exchange reaction in a covalently crosslinked mutant. In: Biochemistry, 38 (1). pp. 423-431.

Velanker, Sameer S and Ray, Soumya S and Gokhale, Rajesh S and Suma, S and Balaram, Hemalatha and Balaram, P and Murthy, MRN (1997) Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design. In: Structure, 5 (6). pp. 751-761.

Karle, Isabella L and Flippen-Anderson, Judith L and Uma, K and Balaram, Hemalatha and Balaram, P (1990) Peptide Design: Influence of a Guest Aib-Pro Segment on the Stereochemistry of an Oligo-Val Sequence-Solution Conformations and Crystal Structure of Boc-(Val)2-Aib-Pro-(Val)3-OMe. In: Biopolymers, 29 (10-11). pp. 1433-1442.

Moretto, V and Crisma, M and Bonora, GM and Toniolo, C and Balaram, Hemalatha and Balaram, P (1989) Comparison of the Effect of Five Guest Residues on the \beta-Sheet Conformation of Host ${(L-Val)}_n$ Oligopeptides. In: Macromolecules, 22 (7). pp. 2939-2944.

Karle, Isabella L and Flippen-Anderson, Judith L and Uma, Kuchibhotla and Balaram, Hemalatha and Balaram, Padmanabhan (1989) \alpha -Helix and Mixed $3_{10}$/ \alpha -helix in Cocrystallized Conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-Ome. In: Proceedings of the National Academy of Sciences of the United States of America, 86 (3). pp. 765-769.

Uma, K and Balaram, Hemalatha and Raghothama, S and Balaram, Padmanabhan (1988) Simultaneous observation of positive and negative nuclear Overhauser effects in oligopeptides due to segmental motio. In: Biochemical and Biophysical Research Communications, 151 (1). pp. 153-157.

Balaram, Hemalatha and Sukumar, M and Balaram, P (1986) Stereochemistry of \alpha-Aminoisobutyric Acid Peptides in Solution: Conformations of Decapeptides with a Central Triplet of Contiguous L-Amino Acids. In: Biopolymers, 25 (11). pp. 2209-2223.

Balaram, Hemalatha and Prasad, Venkataram BV and Balaram, P (1983) Multiple Conformational States of a Pro-Pro Peptide. Solid-State and Solution Conformations of Boc-Aib-Pro-Pro-NHMe. In: Journal of the American Chemical Society, 105 (12). pp. 4065-4071.

Rao, Narasinga BN and Kumar, Anil and Balaram, Hemalatha and Ravi, A and Balaram, P (1983) Nuclear Overhauser Effects and circular Dichroism as Probes of \beta.-turn Conformations in Acyclic and Cyclic Peptides with Pro-X Sequences. In: Journal of the American Chemical Society, 105 (25). pp. 7423-7428.

Prasad, Venkataram BV and Balaram, Hemalatha and Balaram, P (1982) Type II \beta-Turn Conformation of Pivaloyl-L-Prolyl-\alpha-Aminoisobutyryl-N-Methylamide: Theoretical, Spectroscopic, and X-Ray Studies. In: Biopolymers, 21 (7). pp. 1261-1273.

Balaram, Hemalatha and Prasad, B V Venkataram and Balaram, Padmanabhan (1982) Conformational transitions in a Pro-Pro peptide on dissolution of single crystals. In: Biochemical and Biophysical Research Communications, 109 (3). pp. 825-831.

Prasad, BV Venkataram and Balaram, Hemalatha and Balaram, P (1982) Type II beta-turn conformation of pivaloyl-L-prolyl-a-aminoiso-butyryl-N-methylamide: Theoretical, spectroscopic and X-ray studies. In: Biopolymers, 21 (7). pp. 1261-1273.

Prasad, BV Venkataram and Balaram, Hemalatha and Balaram, P (1982) Type II beta-turn conformation of pivaloyl-L-prolyl-alpha-aminoisobutyryl-N-methylamide: Theoretical, spectroscopic, and X-ray studies. In: Biopolymers, 27 (7). pp. 1261-1273.

This list was generated on Thu Oct 23 11:48:35 2014 IST.